Polich updating p300

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Dots represent scores from individual participants. From From P300 Development across the Lifespan: A Systematic Review and Meta-Analysis.

The P300 (P3) wave is an event related potential (ERP) component elicited in the process of decision making.

They found that the amplitude of the positive complex was larger in response to the less probable stimuli, or the one that only had a 1 in 3 chance of appearing.

Another important finding from these studies is that this late positive complex was observed for both the clicks and flashes, indicating that the physical type of the stimulus (auditory or visual) did not matter.

In 1965, Sutton and colleagues published results from two experiments that further explored this late positivity.

They presented subjects with either a cue that indicated whether the following stimulus would be a click or a flash, or a cue which required subjects to guess whether the following stimulus would be a click or a flash.

It is usually elicited using the oddball paradigm, in which low-probability target items are mixed with high-probability non-target (or "standard") items.

In previous studies low frequency repetitive transcranial magnetic stimulation (r TMS) has been used, with positive behavioral and electrophysiological results, for the experimental treatment in ASD.In later studies published in 1967, Sutton and colleagues had subjects guess whether they would hear one click or two clicks.They again observed a positivity around 300 ms after the second click occurred – or would have occurred, in the case of the single click.Outcome measures included behavioral evaluations and reaction time test with event-related potential (ERP) recording.For the main goal of this exploratory study we used r TMS-neurofeedback combination (TMS-NFB, N = 20) and waitlist (WTL, N = 22) groups to examine effects of 18 sessions of integrated r TMS-NFB treatment or wait period) on behavioral responses, stimulus and response-locked ERPs, and other functional and clinical outcomes.

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